Friday, November 29, 2013

Wegner's Granulomatosis Vs Churg-Strauss disease

both cases presentation are identical as they are disease characterized by systemic vasculitis affecting blood vessels in the upper airways , lungs, GIT, kidneys and Joints, so they could be manifested with epistaxis , hemoptysis, haematuria , arthritis and also may feature with glomerulonephritis with hypertension and edema.

both of them are characterized by elevated Anti-neutrophil cytoplasmic antibodies ANCA.

so when you face a presentation with the classic triad of hemoptysis , hematuria and epistaxis, don't have to depend solely on the ANCA test you need to perform a CBC with differential and check for Eosinophilic count , because Churg-Strauss disease is differentiated from Wegner's granulomatosis through eosinophilia, taking into consideration that eosinophilia should be at least 10%

No comments:

Post a Comment