Post operative Fever:

There are various etiologies for the development of postoperative fever:

1-      Pneumonia

2-      Lung collapse!

3-      Wound infection

4-      Transfusions

5-      I.V. lines, Indwelling catheters and UTIs

6-      Deep venous thrombosis

7-      DRUGS:

a-      Penicillin

b-      Macrolide

c-       Isoniazid

d-      Aspirin

e-      Captopril

f-        Allopurinol

How to connect these drugs together? , I wouldn’t lie I can’t understand their pathogenesis and it would be really great if anyone could add why these drugs maybe associated with a postoperative fever, In particular I’m interested how in the world ASPIRIN could be involved in that ?!! : )) maybe I say maybe , Allergic interstitial nephritis ?

Note that, you should know this:

Acute onset of fever which starts within 24 hours postoperatively, consider wound infections, (streptococcal – clostridial – not sure about pseudomonas- but I guess amoxicillin would be enough,

Also consider blood transfusion as an etiology,

Postoperative fever which starts within 3 days postoperatively, Pneumonia is the first thing to consider,

A question I got it wrong because of an information I didn’t know, Incentive spirometry not antibiotics is a better way for prophylaxis against postoperative pneumonia, how? simple concept it increases air flow and clearance of secretions,